▪2023年第4期   述评▪

作者：蔡国靖，方乾，陈桂增，吴晖

单位：中山大学附属第一医院 胃肠外科中心，广东 广州 510080

Authors: Cai Guojing, Fang Qian, Chen Guizeng, Wu Hui

Unit:  Department of Gastrointestinal Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China

摘要：

微转移是胃癌患者复发和预后的潜在影响因素，当前关于胃癌微转移的研究大多集中于淋巴结、外周血和骨髓，鲜见研究关注胃周软组织。胃周软组织直接延伸于胃浆膜，由胃周系膜、韧带、网膜等组织构成，内含脉管、淋巴管、神经等重要结构，作为胃周淋巴结载体，是胃癌淋巴结转移的必经途径。分析胃癌胃周软组织不同成分的微转移情况，有望为淋巴结转移机制提供线索，完善现有胃癌TNM 分期以及丰富预后影响因素。本文就胃周软组织微转移的定义、检测技术、影响因素和临床意义进行探讨。

关键词： 胃癌；胃周软组织；微转移；检测；分期

Abstract：

Micrometastasis is a potential risk factor for recurrence and prognosis of gastric cancer patients. Most current studies about gastric cancer micrometastasis focused on lymph nodes, peripheral blood and bone marrow, but few studies concerned perigastric soft tissues. The perigastric soft tissues extending directly from the gastric serosa are composed of perigastric mesentery, ligament, omentum and other tissues, containing important structures such as vasculature, lymphatic vessels and nerves, which constitute the carrier of perigastric lymph nodes and essential route for lymph node metastasis of gastric cancer. The analysis of perigastric soft tissue micrometastasis is expected to provide clues to the mechanism of lymph node metastasis, complete the existing TNM staging of gastric cancer and enrich the prognostic factors. In this paper, we review the definition, detection techniques, impact factors and clinical significance of perigastric soft tissue micrometastasis.

Key Words:  Gastric cancer; Perigastric soft tissue; Micrometastasis; Detection; Staging

引用格式：蔡国靖, 方乾, 陈桂增, 等. 胃癌胃周软组织微转移临床研究现状[J/CD]. 消化肿瘤杂志(电子版), 2023, 15(4):289-294.