引用文本：陈健聪, 赖佳明. 胰腺癌系统治疗2024年度研究进展[J/CD]. 消化肿瘤杂志（电子版）, 2025, 17(1):23-26.

作者：陈健聪, 赖佳明

单位：中山大学附属第一医院 胆胰外科，广东 广州 510080

Authors：Chen Jiancong，Lai Jiaming

Unit：Department of Pancreatobiliary Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China

摘要：

胰腺癌是预后极差的消化系统恶性肿瘤，具有早期诊断困难、确诊时分期晚、术后复发转移率高等特点。尽管近年来治疗手段不断创新，但其5年生存率仍不足10%。2024年，胰腺癌治疗领域在化疗优化、靶向治疗、免疫治疗及肿瘤电场疗法等方面均取得突破性进展。本文旨在系统总结2024年胰腺癌系统治疗的重要研究成果，为临床实践提供参考依据。

关键词：胰腺癌；系统治疗；化疗；靶向治疗；免疫治疗；肿瘤电场疗法

Abstract：

Pancreatic cancer remains a digestive system malignancy with extremely poor prognosis, characterized by difficulties in early diagnosis, advanced stage at the time of diagnosis, and high rates of postoperative recurrence and metastasis. Despite continuous innovations in treatment modalities in recent years, the five-year survival rate remains below 10%. In 2024, groundbreaking advancements have been made in the field of pancreatic cancer treatment, encompassing chemotherapy optimization, targeted therapy, immunotherapy, and tumor treating fields. This article aims to systematically review the significant research achievements in systemic therapy for pancreatic cancer in 2024, providing a reference for clinical practice.

Key words：Pancreatic cancer; Systemic therapy; Chemotherapy; Targeted therapy; Immunotherapy; Tumor treating fields

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