作者： 刘盛1，李慧琳2

单位：1.中山大学附属第七医院（深圳） 全科医学科，广东 深圳 518107；2.中山大学附属第七医院（深圳） 保健康复中心，广东 深圳 518107

Authors:  Liu Sheng1, Li Huilin2

Unit:  1. General Practice, the Seventh Affiliated Hospital of Sun Yat-sen University (Shenzhen), Shenzhen 518107, Guangdong, China；2. Health Care and Rehabilitation Center, the Seventh Affiliated Hospital of Sun Yat-sen University (Shenzhen), Shenzhen 518107, Guangdong, China

摘要：

本文回顾性分析1例表现为食管溃疡的结外自然杀伤/T细胞淋巴瘤患者的病例资料及诊治经过，并结合相关文献进行分析讨论，以期为此类患者的诊断治疗提供参考。该例患者入院后完善胃镜提示食管多发溃疡，黏膜活检病理结果确诊为结外自然杀伤/T细胞淋巴瘤，予以培门冬酶+吉西他滨+奥沙利铂方案治疗。患者经过5个化疗疗程后再次复查胃镜未见食管溃疡，黏膜活检未见异型细胞，提示完全缓解。

关键词： 食管溃疡；结外自然杀伤/T细胞淋巴瘤；病例报道

Abstract：

1 case data and diagnosis and treatment of a patient with extranodal natural killer/T cell lymphoma presenting with esophageal ulcer were analyzed retrospectively, and the relevant literatures were analyzed and discussed, in order to provide reference for diagnosis and treatment of patients with extranodal natural killer/T-cell lymphoma. After the patient admitted to the hospital, gastroscopy suggested that there were multiple ulcers in the esophagus, and the pathological results of mucosal biopsy confirmed the diagnosis of extranodal natural killer/T -cell lymphoma. The patient was treated with P-Gemox (pegaspargase, gemcitabine and oxaliplatin) regimen, and no esophageal ulcer was found on gastroscopy after 5 courses of chemotherapy, and the mucosal biopsy did not show any heterogeneous cells, suggesting a complete remission.

Key Words:  Esophageal ulcer; Extranodal natural killer/T-cell lymphoma; Case report

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