引用文本：吴启越, 雷子颖, 黄立峰, 等. 腹膜假黏液瘤临床诊治研究进展[J/CD]. 消化肿瘤杂志（电子版）, 2025, 17(2):195-203.

作者：吴启越，雷子颖，黄立峰，丁炳晖，罗嘉莉，王进，唐鸿生

单位：广州医科大学附属肿瘤医院　胃肠外科二区，广东 广州 510095

Authors：Wu Qiyue, Lei Ziying, Huang Lifeng, Ding Binghui, Luo Jiali, Wang Jin, Tang Hongsheng

Unit：Department of Gastrointestinal Surgery Ⅱ, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong, China

摘要：

腹膜假黏液瘤是一种罕见、低度恶性的腹膜肿瘤，常因缺乏典型症状而导致就诊时处于疾病晚期，预后较差。影像学检查主要通过肿瘤大小、位置、形态以及腹腔扩散等特征为腹膜假黏液瘤的诊断提供重要支持，临床上以计算机断层扫描为最常选择。近年来，细胞减灭术结合腹腔热灌注化疗成为腹膜假黏液瘤治疗的核心策略，细胞减灭术通过彻底去除腹膜及相关器官的肿瘤病灶，显著改善局部肿瘤负荷，而腹腔热灌注化疗则通过局部灌注化疗及热疗来进一步加强疗效，降低肿瘤复发的风险，该联合治疗方案已在多项临床研究中显示出显著的疗效，但也面临着技术难度大、术后并发症多等问题。本文对腹膜假黏液瘤的临床诊治研究进展作系统回顾，旨在为未来临床诊疗的进一步发展提供参考。

关键词：腹膜假黏液瘤；细胞减灭术；腹腔热灌注化疗

Abstract：

Pseudomyxoma peritonei (PMP) is a rare and low-grade malignant peritoneal tumor that often presents in the late stages of the disease and has a poor prognosis due to the absence of typical symptoms in the early stages. PMP imaging mainly provides important support for the diagnosis of PMP through the characteristics of tumor size, location, morphology, and abdominal spread, and computed tomography is the most commonly used choice in clinical practice. In recent years, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has become the core strategy for PMP treatment. CRS significantly improves local tumor burden by completely removing tumor lesions in the peritoneum and related organs, while HIPEC further enhances efficacy and reduces the risk of tumor recurrence through local chemotherapy drug infusion and hyperthermia. This combination therapy has shown significant efficacy in multiple clinical studies, but also faces technical difficulties and multiple postoperative complications. This article provides a systematic review of the latest developments in clinical diagnosis and treatment research of PMP.

Key words：Pseudomyxoma peritonei；Cytoreductive surgery；Hyperthermic intraperitoneal chemotherapy

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