作者：余超，王瑜茹，聂宇魁，郭勤平，何若冲

单位：山西医科大学第三医院(山西白求恩医院/山西医学科学院/同济山西医院) 胃肠外科，山西 太原 030032

Authors: Yu Chao, Wang Yuru, Nie Yukui, Guo Qinping, He Ruochong

Unit：Department of Gastrointestinal Surgery, Third Hospital of Shanxi Medical University (Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital), Taiyuan 030032, Shanxi, China

摘要：

结直肠癌发病率呈逐年上升趋势，即使采取根治性手术切除后仍有30%~50%的患者出现复发，一旦复发，患者的生存状况直线下降。若术后能早期预测复发并及时采取干预治疗措施，可显著改善患者的预后和生活质量。本文就当前预测结直肠癌术后早期复发的不同检测方法进行总结讨论，以期为临床医生诊治术后复发患者提供帮助。

关键词：结直肠癌；术后早期复发；标志物；液体活检 

Abstract：

The incidence rate of colorectal cancer is increasing year by year. Even after radical surgery, 30%-50% of patients still have recurrence. Once recurrence occurs, the survival condition of patients declines linearly. Early postoperative prediction of recurrence and timely intervention and treatment measures can significantly improve the prognosis and quality of life of patients. This article discusses the advantages and disadvantages of different detection methods for predicting early postoperative recurrence of colorectal cancer, in order to provide assistance for clinical physicians in diagnosing and treating patients with postoperative recurrence.

Key Words:  Colorectal cancer; Early postoperative recurrence; Marker; Liquid biopsy

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