引用文本：侯雯雯, 王静, 王光荣, 等. 幽门腺腺瘤的内镜病理特征及诊疗进展[J/CD]. 消化肿瘤杂志（电子版）, 2026, 18(3): 460-467.

作者：侯雯雯，王静，王光荣，杨秋子，张梦圆，姚静静，潘圣学，付金栋

单位：日照市人民医院 消化内科，山东 日照 276800

Authors：Hou Wenwen, Wang Jing, Wang Guangrong, Yang Qiuzi, Zhang Mengyuan, Yao Jingjing, Pan Shengxue, Fu Jindong

Unit：Department of Gastroenterology, Rizhao People’s Hospital, Rizhao 276800, Shandong, China

摘要：

幽门腺腺瘤（pyloric gland adenoma, PGA）是一类起源于胃肠道幽门腺的罕见上皮性肿瘤，隶属于胃型分化腺瘤，是世界卫生组织消化系统肿瘤分类界定的具有明确恶性潜能的独立肿瘤实体。PGA好发于胃，多见于胃底、胃体，亦可发生于十二指肠、食管、胆管、胆囊、胰管、直肠、宫颈等部位。本文系统阐述了PGA的分子发病机制、流行病学以及临床、内镜、病理特征与诊疗进展，旨在提高临床医师对该疾病的认知水平，实现早期诊断与精准管理。

关键词：幽门腺腺瘤；癌前病变；内镜特征；病理分型

Abstract：

Pyloric gland adenoma (PGA) is a rare epithelial neoplasm originating from the pyloric glands of the gastrointestinal tract and categorized as a gastric-type differentiated adenoma. As an independent tumor entity with definite malignant potential defined by the World Health Organization (WHO) classification of tumors of the digestive system, PGA occurs predominantly in the stomach, especially in the gastric fundus and body, and can also be found in the duodenum, esophagus, bile duct, gallbladder, pancreatic duct, rectum, cervix and other sites. This article systematically reviews the molecular pathogenesis, epidemiology, clinical manifestations, endoscopic features, pathological characteristics and advances in the diagnosis and management of PGA, aiming to improve the understanding of the disease and achieve early diagnosis and precise management.

Key words：Pyloric gland adenoma; Precancerous lesions; Endoscopic features; Pathological classification

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