作者：刘婧1,2，汪晓东3，黄明君1,2

单位：1.四川大学华西医院 日间服务中心，四川 成都 610041；2.四川大学华西医院/华西护理学院，四川 成都 610041；3.四川大学华西医院 胃肠外科，四川 成都 610041

Authors: Liu Jing1,2，Wang Xiaodong1，Huang Mingjun2,3

Unit: 1.Day Surgery Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China;  2.West China Hospital of Sichuan University/West China School of Nursing, Chengdu 610041, Sichuan, China;  3.Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China

摘要：

低位直肠前切除术是目前中低位直肠癌的主要手术方式，大量患者在术后出现因肠道功能紊乱而导致的众多不良症状，如里急后重、大便失禁等，临床上称为低位前切除综合征（LARS）。LARS影响了患者术后的生活质量，为降低其发生率，更好地进行预后恢复治疗，研究者建立了多种临床预测模型。本文对报道较多的危险因素进行了总结，围绕LARS的临床预测模型展开综述。

关键词：低位直肠癌； 低位前切除综合征； 预测模型； 综述

Abstract：

Low anterior resection now is the major therapy for low and middle rectal cancer. Many patients can easily present a series of adverse symptoms due to anal and intestinal dysfunction after the operation such as tenesmus and fecal incontinence，which is clinically called low anterior resection syndrome （LARS），seriously damaging patients’ life quality. Many researchers have built clinical prediction models in order to make patients better recoveries and to reduce its occurrence or severity. In this paper ，we summarized frequently reported risk factors and reviewed clinical prediction models of LARS.

Key Words:  Low rectal cancer; Low anterior resection syndrome; Prediction model; Review