作者：袁冶1，韩伟凯2，贠陈平1，王天助1，陈彤1，王兴铧1，李涛1

单位：1.山东第一医科大学第三附属医院 神经外科， 山东 济南 250031;  2.山东大学基础医学院 解剖教研室， 山东 济南 250012

Authors: YuanYe1，Han Weikai2，Yun Chenping1，Wang Tianzhu1，Chen Tong1，Wang Xinghua1，Li Tao1

Unit: 1.Neurosurgery，the Third Affiliated Hospital of Shandong First Medical University，Jinan 250031，Shandong，China;  2.Department of Anatomy，School of Basic Medicine，Shandong University，Jinan 250012，Shandong，China

摘要：

本文收集1例胃癌（腺癌）术后22年发生孤立性脑转移的患者病历资料，分析患者的肿瘤病理特征及预后，并对相关报道进行文献复习。胃癌发生脑转移的具体机制尚不明确，目前的治疗方法包括手术切除、全脑放疗、立体定向放疗等联合全身化疗等。但其治疗效果并不理想，胃癌脑转移的早期发现及治疗方法需要进一步探索。

关键词：胃癌； 脑转移； 治疗； 预后

Abstract：

In this article，we collected medical records of a patient who developed isolated brain metastasis 22 years after gastric cancer surgery，analyzed the patient's tumor pathological characteristics and prognosis，and reviewed the literature for external related reports. The specific mechanism of brain metastasis occurring in gastric cancer is not clear，and the current treatment methods include surgical resection，whole brain radiotherapy，stereotactic radiotherapy and other combined systemic chemotherapy. However，these therapeutic effects are not ideal，and the early detection and treatment methods of brain metastasis from gastric cancer need to be further explored.

Key Words:  Gastric cancer； Brain metastasis； Therapy； Prognosis