作者：吴文琪，万远太

单位：武汉科技大学附属天佑医院 消化内科，湖北 武汉 430064

Authors:  Wu Wenqi, Wan Yuantai

Unit:  Department of Gastroenterology, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan 430064, Hubei, China

摘要：

结直肠息肉是结直肠黏膜突向肠腔的隆起性病变,为我国常见多发病,近年来其发病率呈上升趋势。结直肠息肉与结直肠癌的发生高度相关,结直肠癌在肿瘤发病率中排名较高。深入探讨影响结直肠息肉发生发展的危险因素对降低结直肠息肉的发病率及恶变率具有临床指导意义。本文拟从人群特征、生活习惯、幽门螺杆菌感染、代谢综合征及其组分和心理社会因素等方面对结直肠息肉的发生发展展开综述。

关键词：  肠道微生物; 双歧杆菌; 免疫治疗; 机制; 免疫相关不良反应

Abstract：

Colorectal polyp is a protuberant lesion of the colorectal mucosa protrusion into the intestinal cavity, which is a common and frequently occurring disease in China. In recent years, its incidence has been on the rise. Colorectal polyp are highly correlated with the occurrence of colorectal cancer (CRC), and CRC ranks high in the incidence of tumors. To explore the risk factors affecting the occurrence and development of colorectal polyp has clinical guiding significance for reducing the incidence and malignant change rate of colorectal polyp. This paper reviewed the occurrence and development of colorectal polyps from the aspects of population characteristics, living habits, Helicobacter pylori infection, metabolic syndrome (MS), components of MS and psychosocial factors.

Key Words:  Colorectal polyp; Risk factor; Helicobacter pylori; Metabolic syndrome; Psychosocial factors