作者：许继文1，杨力1，郭敏1，王涛2

单位：1.黑龙江中医药大学，黑龙江 哈尔滨 150040；2.黑龙江省中医医院 内分泌科，黑龙江 哈尔滨 150040

Authors: Xu Jiwen1, Yang Li1, Guo Min1, Wang Tao2

Unit: 1.Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang, China；2.Heilongjiang Province Academy of Chinese Medical Sciences Endocrine Department, Harbin 150040,Heilongjiang, China

摘要：

近年来，肿瘤治疗领域取得了一定进展，但肿瘤转移仍是患者死亡的主要原因。肿瘤细胞在转移级联过程中会动态地调节新陈代谢，以适应不同转移阶段的能量需求。因此，靶向转移过程中的代谢特征可能为预防和治疗肿瘤转移提供了机会。本文将首先介绍肿瘤转移过程中与代谢相关的最新进展，然后重点综述与肿瘤代谢密切相关的几种营养物质在肿瘤侵袭、转移过程中的意义，以帮助相关人员了解最新的研究进展，并展望靶向代谢途径的治疗策略的可能性。

关键词：代谢；肿瘤转移；营养物质

Abstract：

In recent years, people have made some progress in the field of tumor treatment, but tumor metastasis is still the main cause of death. In the process of metastasis cascade, tumor cells will dynamically regulate metabolism to meet the energy needs of different metastasis stages. Therefore, targeting the metabolic characteristics in the process of tumor metastasis may provide an opportunity to prevent and treat tumor. This paper will firstly introduce the latest progress related to metabolism in the process of tumor metastasis, and then focus on the significance of several nutrients closely related to tumor metabolism in the process of tumor invasion and metastasis, to help relevant personnel understand the latest research progress and look forward to the possibility of treatment strategies targeting metabolic pathways.

Key Words: Metabolize；Tumor metastasis；Nutrients