作者：熊伟昕，陈健琛

单位：中山大学附属第一医院 胃肠外科中心 健康管理中心，广东 广州 510080

Authors: Xiong Weixin，Chen Jianchen

Unit: Gastrointestinal Surgery Centre, Health Management Center, The First Affiliated Hospital of Sun Yat – sen University, Guangzhou 510080, Guangdong, China

摘要：

目的 探讨预康复术前营养干预对无营养不良风险的胃癌患者围手术期营养状况和术后康复的影响。方法 选取2021年7月至2022年3月期间就诊于中山大学附属第一医院胃肠专科门诊，术前经影像学或病理确诊为胃癌且无营养不良风险的患者101例为研究对象，随机分为对照组48例和观察组53例，对照组患者采用加速康复外科理念常规护理，观察组患者采用基于预康复理念的营养干预。比较两组患者围手术期营养状况及术后早期恢复质量。结果 对照组和观察组患者围手术期营养状况无明显差异；观察组患者C反应蛋白、尿素指标均明显上升，差异有统计学意义（P<0.05）。结论 对无营养不良风险的胃癌患者进行早期额外营养干预可能增加患者肾脏负担和感染风险。

关键词：预康复；胃癌；加速康复外科

Abstract：

Objective To investigate the effect of preoperative nutritional intervention on periopera[1]tive nutritional status and postoperative rehabilitation in gastric cancer patients without malnutrition risk. Method From July 2021 to March 2022, 101 patients diagnosed with gastric cancer by preoperative imaging or pathology without malnutrition risk in the First Affiliated Hospital of Sun Yat-sen University were enrolled in the study and randomly divided into two groups. Patients in the control group （n=48） received routine nursing with the concept of enhanced recovery after surgery （ERAS） and patients in the observation group（n=53 ）received nutritional intervention based on the concept of pre -rehabilitation. The perioperative nutritional status and quality of early postoperative recovery were compared between two groups. Result There was no significant difference in perioperative nutritional status between two groups. CRP and urea indexes of observa[1]tion group were statistically increased. Conclusion Early additional nutritional intervention for gastric cancer patients without malnutrition risk may increase the risk of infection and renal burden.

Key Words: Pre-rehabilitation；Gastric cancer；Enhanced recovery after surgery