作者：杨虹1，陈志辉 2

单位：1.中山大学附属第一医院 手术麻醉中心，广东 广州 510080；2.中山大学附属第一医院 胃肠外科中心，广东 广州 510080

Authors: Yang Hong1，Chen Zhihui2

Unit: 1.Operating Room, The First Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China；2.Center for Gastrointestinal Surgery, The First Hospital of Sun Yat -sen University, Guangzhou 510080, Guangdong, China

摘要：

随着溃疡性结肠炎（UC）发病年龄的增长，UC癌变的风险也会相应地增加。溃疡性结肠炎相关性结直肠癌（UC-CRC）占所有结直肠癌的1%～2%。UC-CRC与一般结直肠癌在流行病学、发病机制、临床特征、诊治方法 及预后监测等方面有明显的区别。本文总结3例典型的UC-CRC病例，分析其临床特点和治疗结果 并复习相关文献，为此类患者的个体化治疗提供参考。

关键词：溃疡性结肠炎；结直肠癌

Abstract：

The risk of ulcerative colitis-associated colorectal cancer （UC-CRC） increases with the duration of UC. The UC-CRC accounts for 1% -2% of all colorectal cancers. There are obvious differences between UC-CRC and non-UC-CRC in epidemiology, pathogenesis, clinical features, diagnosis and treatment strategy, follow-up, and prognosis. We intend to summarize 3 typical UC-CRC cases by analyzing their clinical characteristics and treatment results, and reviewing relevant literature, with an aim to provide the individualized treatment strategy for UC-CRC patients in the future.

Key Words: Ulcerative colitis；Colorectal cancer