作者：陈猛，陈晓明，许荣德，麦启聪

单位：广东省人民医院 肿瘤介入科，广东 广州 510000

Authors:  CHEN Meng, CHEN Xiaoming, XU Rongde, MAI Qicong

Unit:  Interventional Department, Guangdong Provincial People's Hospital, Guangzhou 510000, Guangdong, China

摘要：

循环肿瘤细胞(circulating tumor cell, CTC)是指经过自发或因临床诊疗操作由肿瘤病灶释放进入外周血循环的肿瘤细胞,发生于肿瘤发展全过程,与恶性肿瘤治疗后复发或转移显著相关。CTC检测逐渐成为一种新颖的液体活检技术,有望在对肝恶性肿瘤的早期诊断、指导分期、监测复发转移与预后评估等方面的超越传统影像或血液检测,为肝恶性肿瘤的综合诊疗提供更有力的科学参考。

关键词：  循环肿瘤细胞; 肝恶性肿瘤; 检测; 分型

Abstract：

Circulating tumor cells (CTC) refer to tumor cells that are released from the tumor lesions into the peripheral blood circulation through spontaneous or clinical diagnosis. They occur in the whole process of tumor development and associate with recurrence or metastasis after treatment of malignant tumors significantly. CTC detection has become a novel liquid biopsy technique gradually, which is expected to provide a more powerful scientific reference for comprehensive diagnosis and treatment of hepatocellular carcinoma, like guidance of tumor staging, monitoring recurrence or metastasis and prognosis evaluation of hepatocellular carcinoma.

Key Words:  Circulating tumor cells; Hepatocellular carcinoma; Diagnosis; Classification