作者：卢新泉，易小江，刁德昌，王伟，李洪明，郑燕生，罗立杰，熊文俊，万进

单位：广东省中医院/广州中医药大学第二附属医院 胃肠外科，广东 广州510120

Authors:  LU Xinquan, YI Xiaojiang, DIAO Dechang, WANG Wei, LI Hongming, ZHENG Yansheng, LUO Lijie, XIONG Wenjun, WAN Jin

Unit:  Department of Gastrointestinal (Tumor) Surgery, Guangdong Province Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China

摘要：

目的  探讨老年结直肠癌患者根治术后肺部感染发生情况及危险因素,并提出防治措施。方法  纳入我科2013年1月至2018年7月824例行根治术的老年结直肠癌患者临床资料,回顾性分析其肺部感染发生率及相关危险因素。结果  85例患者术后并发肺部感染,感染率10.32%,高龄、肥胖、白蛋白水平、手术时间延长、开腹手术、合并慢性呼吸道疾病、糖尿病以及有吸烟史患者肺部感染发生率高,差异有统计学意义(P<0.05)。结论  年龄、肥胖、白蛋白水平、手术方式及手术时间、慢性呼吸道疾病、糖尿病、吸烟史与老年结直肠癌患者根治术后并发肺部感染关系密切,其中,患者年龄、肥胖、手术方式、手术时间、慢性呼吸道疾病以及吸烟史为独立危险因素。

关键词： 老年患者; 结直肠癌根治术; 术后肺部感染; 危险因素

Abstract：

Objective  This study aimed to evaluate the incidence and risk factors of postoperative pulmonary infection after radical resection in elderly patients with colorectal cancer, and to propose prevention and treatment measures. Methods  In total,824 elderly patients with colorectal cancer who underwent radical proctocolectomy between January 2013 to July 2008 were analyzed retrospectively for the incidence and risk factors of postoperative pulmonary infection after radical resection. Results  Postoperative pulmonary infection occurred in 85 patients, the infection rate was 10.32 percent. The patients advanced in years and with the obesity, albumin level, operation time extended, open operation, chronic respiratory disease, diabetes and smoking history of patients had high incidence of postoperative pulmonary infection, the difference was statistically significant (P＜0.05). Conclusion  The age, obesity, albumin level, operation mode, operation time, chronic respiratory disease, diabetes and smoking history are closely related to the pulmonary infection after radical resection in elderly colorectal cancer patients, and the age of patients, obesity, operation method, operation time, chronic respiratory disease and smoking history were the independent risk factors.

Key Words:  Elderly patients; Radical proctocolectomy; Postoperative pulmonary infection; Risk factor