作者：肖韵1，杨东杰1，王维佳2，侯洵1，陈连周3，王嘉林3，何裕隆1

单位：1.中山大学附属第一医院 胃肠外科中心，广东 广州 510080；2.中山大学图书馆，广东 广州 510080；3.中山大学附属第一医院 普通外科实验室，广东 广州 510080

Authors:  XIAO Yun1，YANG Dongjie1，WANG Weijia2，HOU Xun1，CHEN Lianzhou3，WANG Jialin3，HE Yulong1

Unit:  1.Department of Gastrointestinal Surgery，the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China； 2. Sun Yat-sen University Libraries, Guangzhou 510080, Guangdong, China； 3. General Surgery Laboratory，the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China

摘要：

随着转化医学发展和精准医疗概念的提出,生物样本库作为临床与科研转化的桥梁作用日益凸现。生物样本库中蕴含着大量可开发与挖掘的科学信息,临床研究样本资源的重要性已经得到了广泛的重视。本文综述了国内外胃肠肿瘤组织标本的标准化采集流程,对组织标本库的采集操作流程中影响标本质量的因素如取材方法、标本离体时间和组织来源差异等做分面总结,以期为胃肠肿瘤组织标本的规范化收集提供参考。

关键词： 胃肠道肿瘤; 组织标本库; 标本收集操作流程

Abstract：

With the development of translational medicine and the introduction of the concept of precision medicine, the biological specimen bank has become increasingly prominent as a bridge between clinical and scientific research. The biological specimen bank contains a large amount of scientific information that can be exploited and excavated. The importance of resources for clinical specimens has been given extensive attention. This article summarizes the standard operating procedure of collecting gastrointestinal tumor tissue specimens both at home and abroad, and summarizes the factors influencing the specimen quality in the collection and operation process of tissue specimen bank, such as the method of resection specimens of gastrointestinal tumor, the ex vivo ischemia time and the differences between organizations of different origins, in order to provide a reference for the standardized collection of gastrointestinal tumor tissue specimens.

Key Words:  Gastrointestinal tumor; Tissue bank; Specimen collection process